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Rice University

Fundamentals of Immunology: Complement, MHC I and II, T Cells, and Cytokines

Course 2 is a four-course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material. This is the second half of the journey through the defenses your body uses to keep you healthy. In the first part we learned about innate immunity and B cell function. The second part covers T cell function and coordination of the immune response. Fundamentals of Immunology: Complement, MHC I and II, T Cells, and Cytokines builds on the first course to describe the functions of Complement, MHC presentation to T cells, T cell development and signaling. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. This course includes the structure of both MHC proteins and T cell receptors and the sources of variation. The course provides animations of gene rearrangement, developmental processes and signal cascades. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline. What You’ll Learn: How complement uses adaptive and innate triggers to target pathogens. The detailed structure and coding of MHC proteins and both alpha-beta and gamma delta receptors and how these proteins interact to initiate an adaptive immune response. The basics of signaling, and the varieties of external receipt and internal activation pathways. We bine the process of putting together how signals and crosstalk control the activity of the immune system.

Status: Molecular Biology
Status: Immunology
IntermediateCourse26 hours

Featured reviews

RH

5.0Reviewed Jan 12, 2020

This course helps me get a basic understanding of immunology. It is beneficial for my further research.

VV

5.0Reviewed Mar 30, 2020

Excellent module which covers in depth knowledge even at molecular level

DS

5.0Reviewed Dec 14, 2019

lectures are good. may have to go through the course guide provided before final exam

RM

5.0Reviewed Jun 7, 2020

Incredible and amazing. There's no words to praise and thank enough for this astonishing course. The only zero I could see is the chance of you don't like it.

AA

4.0Reviewed Jun 25, 2020

This course is good and it has built my interest in immunology.

MN

5.0Reviewed Mar 5, 2020

Amazing lecturer! I will be keep on coming back to the material! very challenging exams and a lot to learn! Absolutely turned on my curiosity mood! Deeply thankful for the course!

LI

5.0Reviewed Oct 25, 2020

Dr. Novotny did a great job in explaining complicated and daunting concepts in an easy to follow and fun way.

MA

5.0Reviewed Nov 9, 2023

Exact and insightful course that provides primary and advanced material for learners. Thank you

WF

4.0Reviewed Jul 10, 2022

Not all the learning points are clear. It seems impossible to know the study points completely.

UU

5.0Reviewed Apr 23, 2021

It s very useful. Actually I learnt many things regarding Tcell and signalling . Worth it....

MP

4.0Reviewed Jan 10, 2020

A good course, but the impression is spoiled by minor flaws. The quality of this course is slightly worse than that of the first part.

IS

5.0Reviewed Apr 7, 2020

Amazing course! Very complex material is explained in a logical and simple way using examples and analogues, which makes it easier to remember.

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