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Johns Hopkins University

One Health Investigations of Outbreaks and Spillover Events

One Health is the concept that human, animal and environmental health are interconnected. Outbreaks of zoonoses, vector-borne diseases, or those related to contamination of the environment are best investigated using a multi-disciplinary One Health approach. Outbreaks of emerging zoonotic infectious diseases where infections in multiple species – from humans, to livestock, to wildlife – may only be well understood if a One Health approach is used. Investigations of spillover events – where a human or new animal species has been infected by a virus, bacteria, or parasite – also require a One Health approach. Beyond infectious diseases, the environment can be contaminated by heavy metals, industrial pollution and other toxins, which can pose a risk to both human and animal health. In order to protect human and animal health from these threats, One Health approaches can be integrated into outbreak investigations and spillover investigations to improve our mechanistic understanding of their proximal and distal causes leading to insights about how they can be prevented.

Status: Investigation
Status: Environmental Monitoring
Course17 hours

Featured reviews

R

4.0Reviewed Jul 30, 2025

It would be a 5 except for some of the modules that had lecturers with difficult to understand accents

BL

4.0Reviewed Jul 28, 2025

Valuable information providing insight into One Health stakeholders

LF

5.0Reviewed Jul 11, 2025

A really well put together course. Thoroughly enjoyed working through the course and revisiting aspects of epidemiology and entomology amongst many other interesting modules.

JS

5.0Reviewed Sep 2, 2025

An in depth and eye opening lesson in human disease caused by spillover. Great historical references as well as insight in to current conditions.

SA

5.0Reviewed Jul 25, 2025

I found this course very informative, it helped to solidify my understanding of the roles One Health has in these investigations with spillover events.

CG

4.0Reviewed Sep 27, 2025

Amazing content. Speakers were sometimes hard to understand, particularly on podcasts.

MS

5.0Reviewed Jun 21, 2025

Concise with good examples of "real" world problem-solving

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